2017-03-31 14:40:392025-05-12 03:09:21
locus
BSU13930
BSU_13930
geneLength
1026
1029
outlinks
bsu
BSU13930
BSU_13930
Gene
Coordinates
1,461,770 -> 1,462,798
1,461,770 → 1,462,798
The protein
Catalyzed reaction/ biological activity
repairs a special thymine dimer (5-thyminyl-5,6-dihydrothymine), which is commonly called spore photoproduct at the early germination phase
repairs a special thymine dimer (5-thyminyl-5,6-dihydrothymine), which is commonly called spore photoproduct at the early germination phase
(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine in DNA --> thymidine dimer in DNA (according to UniProt)
The protein
[SW|Cofactors]
contains a [4Fe-4S] cluster, uses the [4Fe-4S] cluster to reduce SAM
Fe-S cluster [pubmed|29292548]
uses the [4Fe-4S] cluster to reduce SAM
Biological materials
Mutant
BP130 (del ''splB''::''spc''), available in [SW|Fabian Commichau]'s lab
BP130 (Δ''splB''::''spc''), available in [SW|Fabian Commichau]'s and [SW|Jörg Stülke]'s labs [pubmed|30054368]
BKE13930 (Δ[[gene|splB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE13930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGCCACATCCTTTTC, downstream forward: _UP4_TTCACTTAAACGGGCTGTTG
BKK13930 (Δ[[gene|splB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGCCACATCCTTTTC, downstream forward: _UP4_TTCACTTAAACGGGCTGTTG
References
Original publications
Gene
Phenotypes of a mutant
sensitive to blue light-induced DNA damage [pubmed|30054368]
The protein
Protein family
[SW|Radical SAM superfamily] (according to UniProt)
The protein
Paralogous protein(s)
[[this]]