SubtiBank SubtiBank
Version comparison:

2017-03-31 14:40:392025-05-12 03:09:21

locus

BSU13930

BSU_13930

geneLength

1026

1029

outlinks

bsu

BSU13930

BSU_13930

Gene

Coordinates

1,461,770 -> 1,462,798

1,461,770 → 1,462,798

The protein

Catalyzed reaction/ biological activity

repairs a special thymine dimer (5-thyminyl-5,6-dihydrothymine), which is commonly called spore photoproduct at the early germination phase

repairs a special thymine dimer (5-thyminyl-5,6-dihydrothymine), which is commonly called spore photoproduct at the early germination phase

(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine in DNA --> thymidine dimer in DNA (according to UniProt)

The protein

[SW|Cofactors]

contains a [4Fe-4S] cluster, uses the [4Fe-4S] cluster to reduce SAM

Fe-S cluster [pubmed|29292548]

uses the [4Fe-4S] cluster to reduce SAM

Biological materials

Mutant

BP130 (del ''splB''::''spc''), available in [SW|Fabian Commichau]'s lab

BP130 (Δ''splB''::''spc''), available in [SW|Fabian Commichau]'s and [SW|Jörg Stülke]'s labs [pubmed|30054368]

BKE13930 (Δ[[gene|splB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE13930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGCCACATCCTTTTC, downstream forward: _UP4_TTCACTTAAACGGGCTGTTG

BKK13930 (Δ[[gene|splB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGCCACATCCTTTTC, downstream forward: _UP4_TTCACTTAAACGGGCTGTTG

References

Original publications

15699190, 8021181, 21671623, 22197590, 23607538, 23799365, 22761404, 16829676, 11470912, 22906093, 16829680, 11902862, 9733691

15699190, 8021181, 21671623, 22197590, 23607538, 23799365, 22761404, 16829676, 11470912, 22906093, 16829680, 11902862, 9733691, 28401144, 30054368

Gene

Phenotypes of a mutant

sensitive to blue light-induced DNA damage [pubmed|30054368]

The protein

Protein family

[SW|Radical SAM superfamily] (according to UniProt)

The protein

Paralogous protein(s)

[[this]]